*Keratin regulation occurs from several different factors including interaction with associated proteins, phosphorylation, glycosylation (The process of adding sugar units such as in the addition of glycine chains to proteins. An occurrence where a carbohydrate is added to a protein molecule, which can occur in the Golgi apparatus), transglutamination (an enzyme that catalyzes the formation of a covalent bond between a free amine group and the gamma-carboxamide group of protein- or peptide-bound glutamate), caspase cleavage (blocks the ability of the AR to induce cell death) and ubiquitination (a protein is inactivated by attaching Ubiquity to it; which acts as a tag that signals the protein-transport machinery to ferry the protein to the proteasome for degradation). These regulatory modalities may occur singularly or in concert to affect keratin organization, distribution, turnover and function.